Negron was born in Glendale, CA on August 1, 1957, the son of Lucy (née Rosario) and Conrad Negron, Sr., a former mayor of Indian Wells, CA. He studied with Lee Strasberg and even had a private seminar with Lucille Ball.
He started stand-up when he was in high school, getting a spot at the Comedy Store and began cutting his as an extra in movies. He made his full film acting debut in 1982’s soap satire Young Doctors in Love as a love-struck, pill-popping, dancing intern.
He was also reknowned for playing Mr. Pizza Guy in Fasts Times at Ridgemont High and Rodney Dangerfield’s son-in-law in Easy Money. In a KCET interview, Negron said, “I became
the alternative everyman in movies.”
Of late, he was fixture in the Los Angeles comedy scene, appearing in Melinda Hill’s web series Romantic Encounters